Randomized Placebo-Control Trial of Arginine Therapy for Treatment of Children with Sickle Cell Disease and Vasoocclusive Pain

Time

Wed, Jun 26 11:45AM
W 14

Title

Randomized Placebo-Control Trial of Arginine Therapy for Treatment of Children with Sickle Cell Disease and Vasoocclusive Pain

Abstract Summary

38 children with SCD hospitalized for 56 pain events at Children's Hospital Oakland in years 2000-2008 were enrolled into this RCT of parenteral/oral L-arginine (100mg/kg TID) or placebo for 5 days or until discharge. Outcomes included total opioid use (mg/kg), pain scores and length of stay (LOS).

Poster Presenter

Claudia R. Morris
DrMed, MD,
Associate Professor of Pediatrics and Emergency Medicine,
Emory University School of Medicine
United States

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