Novel Strategy to Find Drugs for Autosomal Dominant Polycystic Disease

Time

Mon, Jun 15 9:30AM
M 09

Title

Novel Strategy to Find Drugs for Autosomal Dominant Polycystic Disease

Abstract Summary

We treated Pkd2 null mouse embryos with pan-HDAC inhibitors. Further we also genetically inhibited HDAC5 in Pkd1 null mice to see if it is beneficial. Then we performed a screen, using a small pool of FDA approved compounds with well characterized targets using HDAC5 export as a paradigm.

Poster Presenter

Parama Paul
MS,
PhD Student,
Stowers Institute For Medical Research
United States